The NFL opens Week 1 with a Ravens–Bills Sunday Night Football rematch in Orchard Park, eight months after Buffalo’s 27-25 playoff win. Books list Buffalo as a slight home favorite (-1 to -1.5) with the week’s highest total (50.5–52.5). The Ravens lead the series 7-6 and Lamar Jackson has thrived as an underdog. Expect a fast game, loud crowd, and real AFC stakes right out of the gate.